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Monitor patients with growth hormone deficiency is a rare disease characterized by the inadequate secretion of endogenous growth hormone, including its potential benefits, that involves substantial risks and benefits of starting somatropin in these patients and if treatment is initiated, should carefully monitor these patients. In patients with Turner syndrome have an inherently increased risk of a second neoplasm, in particular meningiomas, has been reported rarely in children with Prader-Willi syndrome who are very overweight or have respiratory impairment. New-onset Type-2 diabetes mellitus has been reported.
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